About Us

condenZero was founded 2019 as a spin-off company of the Laboratory for Quantum Matter Research of the University of Zurich in Switzerland. Our field of expertise includes the development and production of scientific instruments and components for research applications in ultra-high vacuum and cryogenic conditions.


Dr. Denys Sutter

CEO, Co-founder

Dominik Biscette

CTO, Co-founder

Damian Bucher

Physics Lab Technician

Dr. Amelia Estry


Prof. Johan Chang

Scientific partner

Andri Wasescha

Intern from ETH


The Swiss Free Electron Laser (SwissFEL) facility is poised to revolutionize our understanding of ultrafast photochemistry, photobiology, and condensed matter dynamics. For x-ray diffraction experiments on quantum matter systems in pulsed magnetic fields (image to the left), no off-the-shelf product could meet the harsh conditions of low temperatures and compact dimensions. Responding to these demands, Dominik Biscette developed a novel cryostat design. By spring 2017, the first prototype was produced, surpassing the desired functionality (see the cool-down curve below). This new design achieved a lower base temperature, faster cooling rate, and reduced physical dimensions, outperforming existing cryostats. In 2019, a patent application for the design principle was filed, and the same year saw the founding of condenZero. The company aims to implement this cutting-edge cryostat technology for cryo-TEM sample holders and other scientific instruments.



New office location

February, 2023

After four years of continuous operation at the Irchel campus of the University of Zurich physics institute, we are moving our headquarters to the Züri.ch Campus. With the growing team and new space requirements for R&D and production, an enlarged office was the logical next step. We are excited to be part of the Züri.ch Campus with other startups next door while still being very close to vital infrastructure at the University of Zurich.

Robin joins condenZero

February, 2023

Similar to Damian, we had known Robin when he worked together with us during his apprenticeship at ETH Zurich
as a physics laboratory technician. As an excellent technical allrounder, we are excited to bring him into the team until the end of this year.

Damian joins condenZero

January, 2023

We have known Damian already since his apprenticeship at ETH Zurich as a physics laboratory technician. He later then joined the Laboratory for Quantum Matter Research at the University of Zurich,
where we continued to work with him regularly. Damian has a broad background in laboratory work in all aspects, such as CAD design, manufacturing & production and is a strong addition to our team.

Safety first

July, 2022

Electron microscopes typically operate with 100-300 keV electrons. That poses a safety aspect and all such microscopes are shielded to protect the users from bremsstrahlung (x-rays). Any change to the microscope setup should therefore be the subject of safety scrutiny. At our recent visit to the Research Centre Juelich, our cryogenic setup was subject to preliminary safety tests with a positive outcome.

Helium transfer line

June, 2022

On the crudest level, a helium transfer line serves to transport liquid helium between two reservoirs. For our TEM
holder, however, the transfer line and cryostat specifications are intimately linked. Vibrations and helium flow control are crucial for successful cryo-microscopy. To optimise these specifications, we have developed a custom-made helium transfer line.

Lighter and slimmer

March, 2022

Our 3rd generation TEM cryo-holder was tested at the Research Centre Juelich at the end of 2021.
From these tests, we found that the driving motors of the Compu Stage were just about strong enough to move the holder. To stay away from this motor strength limit, we have designed our 4th generation holder two times lighter. Our current G4 holder is now weighing only 200 g.

Swiss Innovation Challenge

December, 2021

It was an exciting experience to be part of the 2021 Swiss Innovation Challenge. We learned a lot from the mentoring sessions and we are honoured to be selected as the winner of the 2021 edition. This achievement would not have been possible without our support network. We are grateful to all those supporting condenZero in previous years.

Helium management

November, 2021

Our cryo-TEM holder relies on a manually operated helium flow circuit. This circuit is now electronically automated such that the cryo-TEM holder can be operated remotely. This is especially useful for TEM users as the absence of humans near the microscope reduces vibrations and is detrimental to high-resolution measurements. Our remote helium flow controller can, however, be helpful for any flow cryostat.

InnoBooster, GRS

November, 2021

condenZero is proud and honoured to be supported by the Gebert Rüfstiftung via the InnoBooster program. We trust that this will enable us to consolidate and establish a groundbreaking new line of cryo-TEM products.

CERN BIC & Park Innovaare

November, 2021

We are looking forward to advancing our cryogenic technology for electron microscopy together with cryo-experts from the CERN and the Paul Scherrer Institute (PSI). With Park Innovaare infrastructure, condenZero can strengthen its ties to the PSI and test new cryo-TEM products in a mutually beneficial fashion. 

Lowering helium consumption

July, 2021

While moving forward with the nationalisation of the patent application, condenZero is also making technical progress. Prototyping of cryo-TEM holders aims to meet customer specifications in terms of stability, base temperature and helium consumption. In our most recent prototype iteration, the helium consumption was cut down by 75%. With this fourfold reduction, our cryostats can be operated with sustainable helium flow.

100 fürs Baselbiet

June, 2021

Part of our (sub-contracting) manufacturing will be carried out by Basel-located workshops. The Basellandschaftliche Kantonalbank (BLKB) and the Standortförderung Baselland offer favourable loans through the “100 fürs Baselbiet” program, for which condenZero could qualify.

Venture Kick won

 February, 2021

Today, Venture Kick announced condenZero is a final stage winner! We are greatly honoured by this decision. Certainly this is an important milestone. We are very much looking forward to the next Kickers Camp.


January, 2021

It is with great excitement and honour that we announce our participation in the ESA BIC CH program. We are very much looking forward to developing our connection to space related industries. In particular, we wish to accelerate the use of advanced additive manufacturing technologies for space applications.

Core Coaching

January, 2021

We are grateful to Innosuisse for their decision to help and support condenZero via the core coaching program. On this three-year program, we aim to grow and consolidate. In the first year period, we will be working on our first sales campaign, financial structures and advance our IP strategy.

Bridge Proof-of-Concept

December, 2019

Eleven young researchers were awarded the Proof-of-Concept grant from the Swiss National Science Foundation (SNSF) & Innosuisse. With the project to make a new cryogenics tool for transmission electron microscopy, condenZero is among the selected projects.

Patent Application

February, 2019

While working on a pulsed magnetic field setup for diffraction experiments at SwissFel, Dominik Biscette invented a new type of cryostat. This paved the way for the cryo-TEM development underpinning the activities of condenZero.

Entrepreneur Fellowship

December, 2018

End of 2018, Denys Sutter has been awarded a UZH BioTech-MedTech Entrepreneur Fellowship from the Werner Siemens Foundation to develop a new type of cryo-sample holder for transmission electron microscopy.